KROK 1 2018 – Question 72 · KROK (Medicine) · Pharmacology

A patient has been taking bisacodyl for a long time to treat chronic constipation. However, several weeks later the aperient effect of the drug diminished. What is the possible cause of this?

  1. A. Material cumulation
  2. B. Drug dependence
  3. C. Sensitization
  4. D. Functional cumulation
  5. E. Acquired tolerance
Hint

Ask what happens to the response to the same dose of a drug after weeks of regular use, and what that implies about adaptation.

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