KROK 1 2018 – Question 79 · KROK (Medicine) · Pharmacology

A man with ischemic heart disease has been taking his medicine too often throughout a day, which resulted in poisoning. Examination detects cyanosis of skin and mucosa, sharp drop of blood pressure, tachycardia, and respiratory depression. Blood methemoglobin is high. What type of medicine did the patient overdose on?

  1. A. Adenosine-based drugs
  2. B. Organic nitrates
  3. C. α-adrenergic blockers
  4. D. Calcium channel blockers
  5. E. Myotropic antispasmodics
Hint

Ask which mechanism turns a drug taken for ischemic heart disease into a cause of methemoglobin, and why the pressure falls so sharply.

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