KROK 1 2017 – Question 51 · KROK (Medicine) · Biological Chemistry

Nitrogen is being excreted from the body mainly as urea. When activity of a certain enzyme in the liver is low, it results in inhibition of urea synthesis and nitrogen accumulation in blood and tissues. Name this enzyme:

  1. A. Carbamoyl phosphate synthetase
  2. B. Amylase
  3. C. Aspartate aminotransferase
  4. D. Pepsin
  5. E. Urease
Hint

Ask which liver enzyme sits at the very entrance of the pathway that converts free ammonia into urea, so that low activity of it blocks the whole sequence.

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