KROK 1 2017 – Question 111 · KROK (Medicine) · Biological Chemistry

Depression and emotional disturbances result from the lack of noradrenaline, serotonin, and other biogenic amines in the brain. Their content in the synapses can be increased through administration of antidepressants that inhibit the following enzyme:

  1. A. L-amino acids oxidase
  2. B. Diamine oxidase
  3. C. Phenylalanine 4-monooxygenase
  4. D. Monoamine oxidase
  5. E. D-amino acid oxidase
Hint

Ask which enzymatic reaction normally breaks these biogenic amines down inside the nerve terminal, so that blocking it would leave more of them in the synapse.

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