KROK 1 2017 – Question 59 · KROK (Medicine) · Biological Chemistry

Blood of the patients with diabetes mellitus shows increased content of free fatty acids. Name the most likely cause of this:

  1. A. Accumulation of palmitoyl-CoA in cytosol
  2. B. Decreased activity of plasma phosphatidylcholine-cholesterolacyltransferase
  3. C. Activation of apoA1, apoA2, and apoA4 apolipoprotein synthesis
  4. D. Increased activity of adipose triglyceride lipase
  5. E. Activation of ketone bodies utilization
Hint

Think about what insulin normally restrains in fat depots, and what happens to the stored fat when that restraint is lost.

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