KROK 1 2016 – Question 176 · KROK (Medicine) · Biological Chemistry

Cholesterol content in blood serum of a 12-year-old boy is 25 mmol/l. Anamnesis states hereditary familial hypercholesterolemia caused by synthesis disruption of receptor-related proteins for:

  1. A. High-density lipoproteins
  2. B. Low-density lipoproteins
  3. C. Middle-density lipoproteins
  4. D. Chylomicrons
  5. E. Very low-density lipoproteins
Hint

Ask which plasma cholesterol carrier depends on a cell-surface receptor for its removal, and what happens to its level when that receptor protein is faulty.

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