KROK 1 2016 – Question 31 · KROK (Medicine) · Biological Chemistry
A 16-year-old adolescent is diagnosed with hereditary UDP (uridine diphosphate) glucuronyltransferase deficiency. Laboratory tests revealed hyperbilirubinemia caused mostly by increased blood content of the following substance:
- A. Urobilinogen
- B. Stercobilinogen
- C. Unconjugated bilirubin
- D. Biliverdine
- E. Conjugated bilirubin
Hint
Ask which form of the pigment lies upstream of the blocked glucuronic acid step and therefore accumulates when the enzyme is deficient.
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