KROK 1 2016 – Question 92 · KROK (Medicine) · Biological Chemistry

The key reaction of fatty acid synthesis is production of malonyl-CoA. What metabolite is the source of malonyl-CoA synthesis?

  1. A. Citrate
  2. B. Succinyl-CoA
  3. C. Acetyl-CoA
  4. D. Malonate
  5. E. Acyl-CoA
Hint

Think about which precursor is carboxylated in the committed, ATP-dependent step of fatty acid synthesis.

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