KROK 1 2015 – Question 124 · KROK (Medicine) · Pathomorphology

An HIV-positive patient’s cause of death is acute pulmonary insufficiency resulting from pneumonia. Pathohistological investigation of lungs has revealed interstitial pneumonia, alveolocyte desquamation and metamorphoses: alveolocyte enlargement, large intranuclear inclusions surrounded by lightly-coloured areas. Transformed cells resemble owl’s eye. Name the causative agent of pneumonia:

  1. A. Influenza virus
  2. B. Candida fungi
  3. C. Toxoplasma
  4. D. Cytomegalovirus
  5. E. Pneumococcus
Hint

Link the unusual cell enlargement with a clear halo around nuclear inclusions to the kind of agent that infects cells of an immunocompromised host.

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