KROK 1 2015 – Question 191 · KROK (Medicine) · Pathomorphology
Granulomas containing lymphocytes and macrophages were detected during analysis of skin biopsy material. Among macrophages there are large cells with fat inclusions, which contain microorganisms in spheric packages (Virchow’s cells). The following disease is based on the described type of hypersensitivity:
- A. Tuberculosis
- B. Syphilis
- C. Epidemic typhus
- D. Rhinoscleroma
- E. Leprosy
Hint
Focus on the unusual cell in this granuloma, a lipid-laden macrophage crowded with packed microorganisms, and ask which chronic infection is known for it.
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