KROK 1 2015 – Question 195 · KROK (Medicine) · Pathomorphology

During autopsy of a 9-month-old girl’s body, who died due to severe pneumonia complicated with sepsis, lack of thymus is observed. In the lymph nodes the lymphoid follicles and cortical substance are absent; follicles of spleen are reduced in size with no light zones and plasma cells. What is the cause of such structural changes?

  1. A. Thymus atrophy
  2. B. Thymus hypoplasia
  3. C. Accidental involution of thymus
  4. D. Thymus aplasia
  5. E. Thymus agenesis
Hint

Work out which lymphoid zones are empty and why, then ask whether the thymus was formed at all or was formed and later reduced.

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