KROK 1 2014 – Question 153 · KROK (Medicine) · Biological Chemistry
Decarboxylation of glutamate induces production of gamma-aminobutyric acid (GABA) neurotransmitter. After breakdown, GABA is converted into a metabolite of the citric acid cycle, that is:
- A. Citric acid
- B. Malate
- C. Succinate
- D. Oxaloacetate
- E. Fumarate
Hint
Trace GABA's carbon skeleton through transamination and the oxidation of the aldehyde that forms, and ask at which point of the cycle that chain re-enters.
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