KROK 1 2014 – Question 2 · KROK (Medicine) · Biological Chemistry

Malaria is treated with structural analogs of vitamin B2 (riboflavin). These drugs disrupt the synthesis of the following enzymes in plasmodium:

  1. A. NAD-dependent dehydrogenase
  2. B. Aminotransferase
  3. C. Cytochrome oxidase
  4. D. FAD-dependent dehydrogenase
  5. E. Peptidase
Hint

Trace riboflavin to the coenzyme forms it gives rise to, then ask which class of enzymes in the parasite's redox reactions cannot work without them.

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