KROK 1 2014 – Question 6 · KROK (Medicine) · Biological Chemistry
A 53-year-old male patient is diagnosed with Paget’s disease. The concentration of oxyproline in daily urine is sharply increased, which primarily means intensified disintegration of:
- A. Collagen
- B. Keratin
- C. Fibrinogen
- D. Albumin
- E. Hemoglobin
Hint
Consider which major body protein is unusual in containing this modified amino acid in large amounts, and what rapid bone turnover would release.
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