KROK 1 2013 – Question 141 · KROK (Medicine) · Pathomorphology

Microscopy of the myocardium of a patient who had died from heart failure revealed foci of fibrinoid necrosis located diffusely in the interstitial stroma, and often around the vessels. Such foci were surrounded by lymphocytes, macrophages, histiocytes. Pericardium was found to have signs of sero-fibrinous pericarditis. What is the most likely diagnosis?

  1. A. Cardiosclerosis
  2. B. Rheumatic heart disease
  3. C. Cardiomyopathy
  4. D. Myocardial infarction
  5. E. -
Hint

Combine the perivascular fibrinoid foci ringed by histiocytes with the fibrinous pericardial reaction and ask which systemic inflammatory process of connective tissue fits both.

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