KROK 1 2014 – Question 9 · KROK (Medicine) · Pathomorphology

Autopsy of a dead patient revealed bone marrow hyperplasia of tubular and flat bones (pyoid marrow), splenomegaly (6 kg) and hepatomegaly (5 kg), enlargement of all lymph node groups. What disease are the identified changes typical for?

  1. A. Hodgkin’s disease
  2. B. Chronic myelogenous leukemia
  3. C. Chronic lymphocytic leukemia
  4. D. Polycythemia vera
  5. E. Multiple myeloma
Hint

Pyoid marrow is a sign of very intense marrow proliferation, so consider which disorders cause it and how they differ in spleen size and bone changes.

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