KROK 1 2013 – Question 181 · KROK (Medicine) · Pathomorphology

Histological examination of the biopsy material obtained from the lower third of the esophagus of a 57-year-old male with the symptoms of continuous reflux revealed the change of the stratified squamous epithelium to the single-layer columnar glandular epithelium with signs of mucus production. Specify the pathological process in the mucous membrane:

  1. A. Hypertrophy
  2. B. Organization
  3. C. Hyperplasia
  4. D. Metaplasia
  5. E. Regeneration
Hint

Compare the epithelium before and after chronic reflux injury and ask what kind of adaptive change has occurred in the tissue type itself, not only in the number of cells.

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