KROK 1 2013 – Question 38 · KROK (Medicine) · Pharmacology
A patient with a dislocated shoulder had been admitted to a hospital. With the purpose of skeletal muscle relaxation he was given an injection of relaxant dithylinum acting normally 5-7 minutes. However, the effect of dithylinum in this patient lasted up to 8 hours. What is the most likely cause of the prolonged effect of dithylinum in this patient?
- A. Potentiation by another drug
- B. Reduced activity of microsomal liver enzymes
- C. Reduced drug excretion
- D. Material accumulation of the drug
- E. Genetic deficiency of blood cholinesterase
Hint
Ask how this short-acting relaxant is normally inactivated in the body and what could go wrong with that step in an individual patient.
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