KROK 1 2012 – Question 49 · KROK (Medicine) · Pathophysiology
A patient with a history of chronic glomerulonephritis presents with azotemia, oliguria, hypo- and isosthenuria, proteinuria. What is the leading factor in the pathogenesis of these symptoms development under chronic renal failure?
- A. Tubular hyposecretion
- B. Disturbed permeability of glomerular membranes
- C. Intensification of glomerular filtration
- D. Mass decrease of active nephrons
- E. Intensification of sodium reabsorption
Hint
Consider what chronic glomerulonephritis does over the years to the number of working units in the kidney and how this limits excretion and concentrating ability.
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