KROK 1 2012 – Question 65 · KROK (Medicine) · Pathophysiology

A man with a long-term history of bronchial asthma died from asphyxia. Histological examination of his lungs revealed that the lumens of bronchioles and minor bronchi contained a lot of mucus with some eosinophils. There was also sclerosis of interalveolar septa, dilatation of alveole lumens. What mechanism accounts for the development of hypersensitivity reaction?

  1. A. Reagine reaction
  2. B. Granulomatosis
  3. C. Immune complex reaction
  4. D. Cytotoxic reaction
  5. E. Lymphocyte-mediated cytolysis
Hint

Ask which of the four classic hypersensitivity mechanisms produces immediate bronchospasm and eosinophil-rich secretions.

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