KROK 1 2012 – Question 46 · KROK (Medicine) · Biological Chemistry

After severe viral hepatitis a 4 year old boy presents with vomiting, occasional loss of consciousness, convulsions. Blood test revealed hyperammoniemia. Such condition is caused by a disorder of the following biochemical hepatic process:

  1. A. Activation of amino acid decarboxylation
  2. B. Protein synthesis inhibition
  3. C. Disorder of biogenic amines neutralization
  4. D. Disorder of ammonia neutralization
  5. E. Inhibition of transamination enzymes
Hint

Ask which normal detoxifying function of the liver is lost when the metabolite raised in this blood test cannot be cleared, producing neurological symptoms.

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