KROK 1 2011 – Question 141 · KROK (Medicine) · Biological Chemistry

Tissue inositol triphosphates are generated as a result of the phosphatidylinositol diphosphate hydrolysis and act as secondary agents (mediators) in the mechanism of hormone action. Their effect in cells is directed at:

  1. A. Calcium ion liberation from cellular depot
  2. B. Phosphodiesterase inhibition
  3. C. Protein kinase A activation
  4. D. Protein kinase A inhibition
  5. E. Adenylate cyclase activation
Hint

Remember that the water-soluble product of this membrane lipid hydrolysis diffuses through the cytosol and acts on a store inside the cell, unlike the cyclic AMP system.

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