KROK 1 2011 – Question 86 · KROK (Medicine) · Biological Chemistry
Vitamin B1 deficiency causes disturbance of oxidative decarboxylation of α-ketoglutaric acid. This leads to the impaired synthesis of the following coenzyme:
- A. Flavine adenine dinucleotide
- B. Thiamine pyrophosphate
- C. Nicotinamide adenine dinucleotide
- D. Coenzyme A
- E. Lipoic acid
Hint
Ask which cofactor of the α-ketoglutarate dehydrogenase complex is made from vitamin B1 itself, as opposed to the cofactors that are made from other vitamins.
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