KROK 1 2011 – Question 81 · KROK (Medicine) · Biological Chemistry
A patient has been diagnosed with alkaptonuria. Choose an enzyme whose deficiency can be the reason for this pathology:
- A. Phenylalanine hydroxylase
- B. Dioxyphenylalanine decarboxylase
- C. Glutamate dehydrogenase
- D. Homogentisic acid oxidase
- E. Pyruvate dehydrogenase
Hint
Recall the inborn error of aromatic amino-acid degradation in which urine darkens on standing, and think which enzymatic step of that pathway is missing.
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