KROK 1 2011 – Question 66 · KROK (Medicine) · Biological Chemistry
Jaundice treatment involves administration of barbiturates inducing the synthesis of UDP-glucuronyl transferase. A medicinal effect is caused by the production of:
- A. Direct reacting (conjugated) bilirubin
- B. Biliverdin
- C. Protoporphyrin
- D. Heme
- E. Indirect reacting (unconjugated) bilirubin
Hint
Consider what the induced enzyme attaches to its substrate in the liver cell and what that does to the solubility and excretion of the pigment.
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