KROK 1 2010 – Question 142 · KROK (Medicine) · Biological Chemistry

A 4 year old child with hereditary renal lesion has signs of rickets, vitamin D concentration in blood is normal. What is the most probable cause of rickets development?

  1. A. Increased excretion of calcium
  2. B. Lack of calcium in food
  3. C. Hyperfunction of parathyroid glands
  4. D. Hypofunction of parathyroid glands
  5. E. Impaired synthesis of calcitriol
Hint

A normal vitamin D level with rickets suggests a defect in a later activation step, so ask where the hormonal form is made and what a renal disease would do to it.

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