KROK 1 2011 – Question 5 · KROK (Medicine) · Biological Chemistry

A 46-year-old female patient has a continuous history of progressive muscular (Duchenne’s) dystrophy. Which blood enzyme changes will be of diagnostic value in this case?

  1. A. Adenylate cyclase
  2. B. Creatine phosphokinase
  3. C. Glutamate dehydrogenase
  4. D. Lactate dehydrogenase
  5. E. Pyruvate dehydrogenase
Hint

Ask which enzyme is concentrated in muscle fibres and leaks into serum when the muscle membrane is damaged, and which one is the most muscle-specific.

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