KROK 1 2010 – Question 129 · KROK (Medicine) · Pathophysiology
Examination of a 42 year old patient revealed a tumour of adenohypophysis. Objectively: the patient’s weight is 117 kg, he has moon-like hyperemic face, red-blue striae of skin distension on his belly. Osteoporosis and muscle dystrophy are present. AP is 210/140 mm Hg. What is the most probable diagnosis?
- A. Essential hypertension
- B. Cushing’s disease
- C. Conn’s disease
- D. Cushing’s syndrome
- E. Diabetes mellitus
Hint
Identify the hormone in excess from the physical signs and decide where the primary lesion sits along the hypothalamic-pituitary-adrenal axis.
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