KROK 1 2010 – Question 124 · KROK (Medicine) · Pathophysiology
A couple had a child with Down’s disease. Mother is 42 years old. This disease is most probably caused by the following impairment of prenatal development:
- A. Embryopathy
- B. Blastopathy
- C. Non-specific fetopathy
- D. Specific fetopathy
- E. Gametopathy
Hint
Consider at what moment the chromosomal error arose, before fertilisation, in the first days, during organ formation or later in fetal growth, and how maternal age fits.
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