KROK 1 2010 – Question 38 · KROK (Medicine) · Pathophysiology
A 34 year old woman was diagnosed with hereditary microspherocytic hemolytic anemia (Minkowsky-Shauffard disease). What mechanism caused haemolysis of erythrocytes?
- A. Autoimmune disorder
- B. Membranopathy
- C. Enzymopathy
- D. Hemoglobinopathy
- E. Bone marrow hypoplasia
Hint
Think about which structural component of the red cell is inherited abnormally when the cells become spherical and are trapped and destroyed in the spleen.
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