KROK 1 2010 – Question 77 · KROK (Medicine) · Pathophysiology

A 25 year old Palestinian woman complains of weakness, dizziness, dyspnea. In anamnesis: periodically exacerbating anemia. In blood: Hb - 60 g/l, erythrocytes - 2,5 · 10¹² /l, reticulocytes - 35 ‰ , anisocytosis and poikilocytosis of erythrocytes, a lot of target cells and polychromatophils. What type of anemia is it?

  1. A. Addison-Biermer disease
  2. B. Sickle-cell anemia
  3. C. Minkowsky-Shauffard disease
  4. D. Glucose 6-phosphate dehydrogenase-deficient anemia
  5. E. Thalassemia
Hint

Combine the patient's geographic origin with the target cells, polychromasia and raised reticulocytes to decide which inherited red-cell disorder fits this blood picture.

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