KROK 1 2010 – Question 37 · KROK (Medicine) · Pathophysiology

A 44 year old woman complains of general weakness, heart pain, significant increase of body weight. Objectively: moon face, hirsutism, AP is 165/100 mm Hg, height - 164 cm, weight - 103 kg; the fat is mostly accumulated on her neck, thoracic girdle, belly. What is the main pathogenetic mechanism of obesity?

  1. A. Increased insulin production
  2. B. Reduced glucagon production
  3. C. Increased production of glucocorticoids
  4. D. Reduced production of thyroid hormones
  5. E. Increased mineralocorticoid production
Hint

Match the combination of moon face, hirsutism, hypertension and trunk-centred fat to the hormone excess that explains this body-fat pattern.

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