KROK 1 2007 – Question 160 · KROK (Medicine) · Biological Chemistry
A 1 y.o. child with symptoms of muscle affection was admitted to the hospital. Examination revealed carnitine deficit in muscles. Biochemical base of this pathology is disturbed process of:
- A. Lactic acid utilization
- B. Substrate phosphorylation
- C. Transporting of fatty acids to mitochondrions
- D. Regulation of Ca2+ rate in mitochondrions
- E. Actin and myosin synthesis
Hint
Carnitine is a carrier molecule, so think about which fuel molecules must be moved across the mitochondrial membrane before muscle can oxidise them.
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