KROK 1 2009 – Question 7 · KROK (Medicine) · Biological Chemistry
A mother consulted a doctor about her 5-year-old child who develops erythemas, vesicular rash and skin itch under the influence of sun. Laboratory studies revealed decreased iron concentration in the blood serum, increased uroporphyrinogen I excretion with the urine. What is the most likely inherited pathology in this child?
- A. Methemoglobinemia
- B. Coproporphyria
- C. Hepatic porphyria
- D. Intermittent porphyria
- E. Erythropoietic porphyria
Hint
Focus on the uroporphyrinogen isomer found in the urine and on which tissue's haem synthesis it implicates, in a child with photosensitivity since early life.
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