KROK 1 2009 – Question 20 · KROK (Medicine) · Biological Chemistry

A 62-year-old female patient has developed a cataract (lenticular opacity) secondary to the diabetes mellitus. What type of protein modification is observed in case of diabetic cataract?

  1. A. ADP-ribosylation
  2. B. Glycosylation
  3. C. Phosphorylation
  4. D. Limited proteolysis
  5. E. Methylation
Hint

Consider what sustained high blood sugar does chemically to the free amino groups of long-lived lens proteins.

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