KROK 1 2007 – Question 158 · KROK (Medicine) · Pathomorphology
An experimental animal was first sensibilized whereupon an antigen dose was introduced subcutaneously. This injection resulted in the development of a fibrinous inflammation with alteration of vessel walls, basal substance and fibrous structures of connective tissue in form of mucoid and fibrinoid swelling and necrosis. What immunological reaction took place?
- A. Normergic reaction
- B. Granulomatosis
- C. Reaction of transplantation immunity
- D. Delayed-type hypersensitivity
- E. Immediate hypersensitivity
Hint
Think of a local Arthus-type reaction: it develops fast after repeated exposure and damages vessel walls through antigen-antibody complexes rather than through T cells.
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