KROK 1 2007 – Question 164 · KROK (Medicine) · Pathomorphology

Microscopical renal examination of a 36 y.o. woman who died from renal insufficiency revealed in the glomerules proliferation of capsule nephrothelium as well as of podocytes and phagocytes accompanied by formation of "crescents", capillary loop necrosis, fibrinous thrombi in their lumens; sclerosis and hyalinosis of glomerules, atrophy of tubules and fibrosis of renal stroma. What is the most probable diagnosis?

  1. A. Acute glomerulonephritis
  2. B. Subacute glomerulonephritis
  3. C. Focal segmentary sclerosis
  4. D. Chronic glomerulonephritis
  5. E. Membranous nephropathy
Hint

Crescents made of proliferating capsular epithelium with capillary loop necrosis point to a rapidly progressing course ending in renal failure; think which form of glomerulonephritis is defined by this.

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