KROK 1 2007 – Question 52 · KROK (Medicine) · Biological Chemistry

Examination of a patient with frequent hemorrhages from internals and mucous membranes revealed proline and lysine being a part of collagene fibers. What vitamin absence caused disturbance of their hydroxylation?

  1. A. Vitamin A
  2. B. Vitamin E
  3. C. Vitamin K
  4. D. Vitamin C
  5. E. Thiamine
Hint

Think about the water-soluble cofactor that keeps the iron of prolyl and lysyl hydroxylases reduced, and whose lack leads to bleeding gums and fragile capillaries.

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