KROK 1 2007 – Question 102 · KROK (Medicine) · Biological Chemistry
To prevent postoperative bleeding a 6 y.o. child was administered vicasol that is a synthetic analogue of vitamin K. Name post-translational changes of blood coagulation factors that will be activated by vicasol:
- A. Polymerization
- B. Partial proteolysis
- C. Carboxylation of glutamin acid
- D. Phosphorylation of serine radicals
- E. Glycosylation
Hint
Recall that vitamin K acts as a cofactor in modifying particular amino acid residues of clotting factors II, VII, IX and X so that they can bind calcium.
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