KROK 1 2007 – Question 109 · KROK (Medicine) · Biological Chemistry

A 4 y.o. boy has had recently serious viral hepatitis. Now there are such clinical presentations as vomiting, loss of consciousness, convulsions. Blood analysis revealed hyperammoniemia. Disturbance of which biochemical process caused such pathological condition of the patient?

  1. A. Activation of aminoacid decarboxylation
  2. B. Increased putrefaction of proteins in bowels
  3. C. Inhibition of transamination enzymes
  4. D. Disturbed neutralization of ammonia in liver
  5. E. Disturbed neutralization of biogenic amines
Hint

Think about which organ normally converts the nitrogen waste released from amino acid breakdown into a harmless excretable compound, and what severe hepatitis does to that organ.

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