KROK 1 2008 – Question 189 · KROK (Medicine) · Biological Chemistry
Pharmacological effects of antidepressants are connected with inhibition of an enzyme catalyzing biogenic amines noradrenaline and serotonine in the mitochondrions of cerebral neurons. What enzyme participates in this process?
- A. Decarboxylase
- B. Peptidase
- C. Transaminase
- D. Monoamine oxidase
- E. Lyase
Hint
Neurotransmitter amines are inactivated by oxidative removal of the amino group inside mitochondria; think which enzyme does this and why blocking it raises amine levels.
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