KROK 1 2008 – Question 73 · KROK (Medicine) · Pharmacology

Mother of a 2 year old child consulted a stomatologist. In the period of pregnancy she was irregularly taking antibiotics for an infectious disease. Examination of the child revealed incisor destruction, yellow enamel, brown rim around the dental cervix. What drug has apparent teratogenic effect?

  1. A. Octadine
  2. B. Ampiox
  3. C. Xantinol nicotinate
  4. D. Furosemide
  5. E. Doxycycline
Hint

Decide which of the listed drugs are antibiotics at all, and which antibiotic group is known to damage the mineralising tissues of the fetus (teeth and bone) when given in pregnancy.

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