KROK 1 2008 – Question 48 · KROK (Medicine) · Microbiology, Virology, and Immunology

In order to estimate toxigenity of diphtheria agents obtained from patients the cultures were inoculated on Petri dish with nutrient agar on either side of a filter paper strip that was put into the centre and moistened with antidiphtheric antitoxic serum. After incubation of inoculations in agar the strip-like areas of medium turbidity were found between separate cultures and the strip of filter paper. What immunological reaction was conducted?

  1. A. Rings precipitation reaction
  2. B. Precipitation gel reaction
  3. C. Coomb’s test
  4. D. Opsonization reaction
  5. E. Agglutination reaction
Hint

Consider the physical state of the antigen (soluble toxin or whole cells), the medium in which the reaction takes place (liquid, tube or agar) and what visible product forms; match these features with the listed reactions.

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