KROK 1 2008 – Question 116 · KROK (Medicine) · Microbiology, Virology, and Immunology

A culture of monkey cells (Vero) and a group of mouse sucklings were infected with an inoculum taken from a child with provisional diagnosis "enterovirus infection". There was no cytopathic effect on the cell culture but mouse sucklings died. What enteric viruses might have caused disease of this child?

  1. A. Coxsackie A
  2. B. Polioviruses
  3. C. Unclassified enteric viruses 68-71
  4. D. Coxsackie B
  5. E. ECHO virus
Hint

Consider which group of enteroviruses fails to produce visible changes in monkey cell culture yet is lethal for newborn mice.

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