KROK 1 2008 – Question 66 · KROK (Medicine) · Microbiology, Virology, and Immunology
48 hours after tuberculine test (Mantoux test) a child had a papule 10 mm in diameter on the spot of tuberculine injection. What hypersensitivity mechanism underlies these changes?
- A. Cellular cytotoxicity
- B. Granulomatosis
- C. Immunocomplex cytotoxicity
- D. Antibody-dependent cytotoxicity
- E. Anaphylaxy
Hint
Pay attention to the time course: a papule at 48 hours is a delayed reaction. Compare this with how quickly antibody-mediated and IgE-mediated reactions appear, then decide which listed mechanism fits a slow reaction.
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