KROK 1 2021 – Question 113 · KROK (Medicine) · Pharmacology

A 50-year-old man has undergone a surgery for gastric cancer. Complex anesthesia included dithylin (suxamethonium iodide). After the surgery was over, dithylin effect continued. Why is proserine (neostigmine) contraindicated in case of dithylin overdose?

  1. A. Increases synaptic membrane depolarization
  2. B. Reduces acetylcholine effect
  3. C. Causes intestinal colic
  4. D. Reactivates acetylcholinesterase
  5. E. May cause bronchospasm
Hint

Remember what kind of neuromuscular block suxamethonium produces and what an anticholinesterase does to the acetylcholine level at the end plate.

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