KROK 1 2021 – Question 53 · KROK (Medicine) · Pharmacology
A patient with essential hypertension was prescribed hydrochlorothiazide as a part of complex therapy. What mechanism of drug action facilitates a decrease in blood pressure in this case?
- A. Decreased excretion of sodium ions and water
- B. Carbonic anhydrase blockade
- C. Increased production of angiotensin II
- D. Increased excretion of sodium ions and water
- E. Calcium channel blockade
Hint
Think about the nephron segment where thiazides act and how that changes extracellular fluid volume, cardiac output and eventually vascular resistance during long-term treatment.
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