KROK 1 2021 – Question 16 · KROK (Medicine) · Biological Chemistry
Wernicke-Korsakoff syndrome often develops in chronic alcoholics, who have a low-vitamin diet. Decreased transketolase activity can be observed in the course of this disease. What vitamin deficiency causes this development?
- A. Riboflavin
- B. Thiamine
- C. Retinol
- D. Cobalamin
- E. Niacin
Hint
Transketolase is a pentose phosphate pathway enzyme that needs a coenzyme derived from a vitamin which is poorly absorbed and quickly depleted in alcohol abuse.
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