KROK 1 2021 – Question 35 · KROK (Medicine) · Biological Chemistry
A 3-year-old child after a past case of severe viral infection presents with recurrent vomiting, loss of consciousness, and seizures. Blood testing reveals hyperammonemia. What is the likely cause of such changes in the biochemical parameters of the child's blood?
- A. Disturbed ammonia neutralization in the Krebs cycle
- B. Activation of amino acid decarboxylation processes
- C. Increased putrefaction of proteins in the intestine
- D. Disturbed neutralization of biogenic amines
- E. Disturbed ammonia neutralization in the ornithine cycle
Hint
Think about the liver pathway that converts toxic ammonia into a non-toxic nitrogen end-product excreted by the kidneys, and what happens to blood ammonia when it is impaired.
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