KROK 1 2021 – Question 15 · KROK (Medicine) · Pathophysiology

According to the Schade’s physicochemical theory, hyperosmia, hyperonchia, and acidosis can be observed in the area of inflammation. The development of hyperosmia is, to an extent, associated with the increasing concentration of K⁺ in the inflamed area. What causes the hyperkalemia of the inflammatory exudate?

  1. A. Excess of Ca²⁺ ions
  2. B. Intensive destruction of damaged cells
  3. C. Inhibition of glycogenolysis in the area of inflammation
  4. D. Activation of proliferative processes
  5. E. Increased permeability of the vascular wall
Hint

Potassium is mostly inside cells, so think about what must happen to cells in the injured focus to flood the exudate with it.

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